| | 1995-97 | Rate/100,000 |
| Name | Deaths | Population | Crude | Age Adjusted |
| CLARK (JEFFERSONVILLE), IN - SCOTT, IN | 12 | 359,470 | 3.3 | 3.3 |
| HOWARD (KOKOMO), IN - CASS, IN | 13 | 433,174 | 3.0 | 2.8 |
| WAYNE, IN - FAYETTE, IN | 9 | 328,661 | 2.7 | 2.5 |
| MARION (INDIANAPOLIS), IN - HENDRICKS, IN | 91 | 3,670,042 | 2.5 | 2.4 |
| VERMILION, IL - EDGAR, IL | 13 | 410,535 | 3.2 | 2.3 |
| GRANT, IN - WABASH, IN | 11 | 437,594 | 2.5 | 2.1 |
| ELKHART (ELKHART), IN - KOSCIUSKO, IN | 18 | 750,017 | 2.4 | 2.1 |
| BARTHOLOMEW, IN - JACKSON, IN | 11 | 503,861 | 2.2 | 2.0 |
| VIGO (TERRE HAUTE), IN - SULLIVAN, IN | 17 | 633,142 | 2.7 | 1.9 |
| DUBOIS, IN | 3 | 121,896 | 2.5 | 1.9 |
| HAMILTON (CINCINNATI), OH - BUTLER, OH | 95 | 4,921,053 | 1.9 | 1.7 |
| BOONE (LEBANON), IN | 3 | 132,090 | 2.3 | 1.7 |
| MADISON (ANDERSON), IN - HAMILTON, IN | 13 | 877,233 | 1.5 | 1.7 |
| LAKE (GARY), IN - PORTER, IN | 40 | 2,077,527 | 1.9 | 1.7 |
| HENRY (NEW CASTLE), IN - HANCOCK, IN | 6 | 314,764 | 1.9 | 1.7 |
| DELAWARE (MUNCIE), IN - RANDOLPH, IN | 10 | 496,691 | 2.0 | 1.7 |
| VANDERBURGH (EVANSVILLE), IN - GIBSON, IN | 22 | 961,471 | 2.3 | 1.7 |
| LA PORTE, IN - STARKE, IN | 6 | 412,616 | 1.5 | 1.6 |
| ST. JOSEPH (SOUTH BEND), IN - MARSHALL, IN | 17 | 1,050,589 | 1.6 | 1.5 |
| LAWRENCE, IN - ORANGE, IN | 3 | 201,117 | 1.5 | 1.5 |
| KNOX, IN - DAVIESS, IN | 7 | 399,351 | 1.8 | 1.4 |
| TIPPECANOE (LAFAYETTE), IN - CLINTON, IN | 13 | 701,649 | 1.9 | 1.4 |
| ALLEN (FORT WAYNE), IN - WHITLEY, IN | 21 | 1,517,049 | 1.4 | 1.3 |
| JEFFERSON (MADISON), IN - DEARBORN, IN | 6 | 417,843 | 1.4 | 1.3 |
| FLOYD (NEW ALBANY), IN - HARRISON, IN | 6 | 438,438 | 1.4 | 1.2 |
| DAVIESS (OWENSBORO), KY - OHIO, KY | 8 | 467,359 | 1.7 | 1.1 |
| MONTGOMERY, IN | 2 | 113,132 | 1.8 | 1.0 |
| MONROE (BLOOMINGTON), IN - GREENE, IN | 6 | 569,353 | 1.1 | 0.9 |
| WELLS, IN - JAY, IN | 3 | 369,575 | 0.8 | 0.7 |
