| | 1996-98 | Rate/100,000 | |
| Name | Deaths | Population | Crude | Age Adjusted | |
| PAGE, IA-FREMONT, IA -HSA# 644 | 10 | 96,826 | 10.3 | 9.0 | UNSTABLE |
| BLACK HAWK (WATERLOO), IA-FAYETTE, IA -HSA# 557 | 23 | 647,566 | 3.6 | 3.1 |
| POTTAWATTAMIE (COUNCIL BLUFFS), IA-SHELBY, IA -HSA# 596 | 16 | 448,686 | 3.6 | 3.0 | UNSTABLE |
| LUCAS, IA-WAYNE, IA -HSA# 645 | 2 | 47,508 | 4.2 | 2.8 | UNSTABLE |
| LA CROSSE (LA CROSSE), WI-MONROE, WI -HSA# 290 | 21 | 684,750 | 3.1 | 2.6 |
| LEE, IA-HANCOCK, IL -HSA# 367 | 6 | 201,973 | 3.0 | 2.4 | UNSTABLE |
| DUBUQUE (DUBUQUE), IA-STEPHENSON, IL -HSA# 302 | 14 | 536,666 | 2.6 | 2.3 | UNSTABLE |
| MINNEHAHA (SIOUX FALLS), SD-LAKE, SD -HSA# 544 | 17 | 710,645 | 2.4 | 2.2 | UNSTABLE |
| OLMSTED (ROCHESTER), MN-WINONA, MN -HSA# 552 | 23 | 899,636 | 2.6 | 2.2 |
| WOODBURY (SIOUX CITY), IA-BUENA VISTA, IA -HSA# 560 | 16 | 629,462 | 2.5 | 2.2 | UNSTABLE |
| CLAY, IA-DICKINSON, IA -HSA# 625 | 4 | 130,880 | 3.1 | 2.2 | UNSTABLE |
| WAPELLO, IA-MAHASKA, IA -HSA# 589 | 8 | 305,086 | 2.6 | 2.2 | UNSTABLE |
| CERRO GORDO, IA-KOSSUTH, IA -HSA# 556 | 9 | 320,719 | 2.8 | 2.1 | UNSTABLE |
| MARTIN, MN-EMMET, IA -HSA# 626 | 2 | 99,301 | 2.0 | 2.0 | UNSTABLE |
| SIOUX, IA -HSA# 672 | 2 | 93,760 | 2.1 | 1.9 | UNSTABLE |
| SCOTT (DAVENPORT), IA-MUSCATINE, IA -HSA# 641 | 11 | 596,137 | 1.8 | 1.9 | UNSTABLE |
| LINN (CEDAR RAPIDS), IA-JOHNSON, IA -HSA# 545 | 22 | 1,184,252 | 1.9 | 1.8 |
| DES MOINES, IA-HENRY, IA -HSA# 340 | 4 | 211,988 | 1.9 | 1.6 | UNSTABLE |
| OBRIEN, IA-OSCEOLA, IA -HSA# 652 | 2 | 65,942 | 3.0 | 1.6 | UNSTABLE |
| POLK (DES MOINES), IA-MARION, IA -HSA# 546 | 24 | 1,666,569 | 1.4 | 1.4 |
| CARROLL, IA-CALHOUN, IA -HSA# 633 | 2 | 134,937 | 1.5 | 1.4 | UNSTABLE |
| WEBSTER, IA-HUMBOLDT, IA -HSA# 585 | 3 | 174,286 | 1.7 | 1.3 | UNSTABLE |
| MARSHALL, IA-TAMA, IA -HSA# 679 | 3 | 169,323 | 1.8 | 1.2 | UNSTABLE |
| CRAWFORD, IA -HSA# 681 | 1 | 49,358 | 2.0 | 1.2 | UNSTABLE |
| STORY, IA-HAMILTON, IA -HSA# 606 | 6 | 448,466 | 1.3 | 1.2 | UNSTABLE |
| CLINTON, IA-WHITESIDE, IL -HSA# 361 | 5 | 381,289 | 1.3 | 1.1 | UNSTABLE |
| POWESHIEK, IA -HSA# 686 | 1 | 56,651 | 1.8 | 1.0 | UNSTABLE |
| CRAWFORD, WI-CLAYTON, IA -HSA# 350 | 2 | 161,255 | 1.2 | 1.0 | UNSTABLE |
| MONTGOMERY, IA-ADAMS, IA -HSA# 647 | 1 | 48,825 | 2.0 | 0.9 | UNSTABLE |
| MITCHELL, IA -HSA# 665 | 0 | 33,191 | 0.0 | 0.0 | UNSTABLE |
| WINNESHIEK, IA -HSA# 395 | 0 | 62,712 | 0.0 | 0.0 | UNSTABLE |
| APPANOOSE, IA-DAVIS, IA -HSA# 649 | 0 | 66,001 | 0.0 | 0.0 | UNSTABLE |
| FLOYD, IA-CHICKASAW, IA -HSA# 634 | 0 | 89,660 | 0.0 | 0.0 | UNSTABLE |
| GREENE, IA-GUTHRIE, IA -HSA# 617 | 0 | 64,598 | 0.0 | 0.0 | UNSTABLE |
