| | 1996-98 | Rate/100,000 | |
| Name | Deaths | Population | Crude | Age Adjusted | |
| LINCOLN, MS-COPIAH, MS -HSA# 511 | 13 | 181,139 | 7.2 | 6.8 | UNSTABLE |
| ADAMS, MS-CONCORDIA, LA -HSA# 435 | 11 | 235,681 | 4.7 | 4.4 | UNSTABLE |
| FORREST, MS-COVINGTON, MS -HSA# 409 | 17 | 453,817 | 3.7 | 4.2 | UNSTABLE |
| LEFLORE, MS-BOLIVAR, MS -HSA# 487 | 15 | 370,904 | 4.0 | 4.1 | UNSTABLE |
| OKTIBBEHA, MS-WEBSTER, MS -HSA# 484 | 7 | 236,011 | 3.0 | 3.3 | UNSTABLE |
| PIKE, MS-MARION, MS -HSA# 477 | 9 | 276,525 | 3.3 | 3.1 | UNSTABLE |
| WILKINSON, MS -HSA# 525 | 1 | 27,630 | 3.6 | 3.1 | UNSTABLE |
| SHELBY (MEMPHIS), TN-PANOLA, MS -HSA# 146 | 90 | 3,414,127 | 2.6 | 2.7 |
| LOWNDES, MS-CLAY, MS -HSA# 461 | 8 | 333,162 | 2.4 | 2.6 | UNSTABLE |
| LAUDERDALE, MS-NEWTON, MS -HSA# 412 | 14 | 556,789 | 2.5 | 2.6 | UNSTABLE |
| HINDS (JACKSON), MS-RANKIN, MS -HSA# 411 | 37 | 1,605,126 | 2.3 | 2.4 |
| LAWRENCE, MS-JEFFERSON DAVIS, MS -HSA# 504 | 2 | 80,426 | 2.5 | 2.4 | UNSTABLE |
| WASHINGTON, MS-SHARKEY, MS -HSA# 488 | 5 | 221,495 | 2.3 | 2.3 | UNSTABLE |
| LEE, MS-PRENTISS, MS -HSA# 418 | 12 | 525,670 | 2.3 | 2.3 | UNSTABLE |
| YAZOO, MS -HSA# 533 | 2 | 76,057 | 2.6 | 2.3 | UNSTABLE |
| COAHOMA, MS-QUITMAN, MS -HSA# 422 | 4 | 168,614 | 2.4 | 2.1 | UNSTABLE |
| JONES, MS-WAYNE, MS -HSA# 455 | 7 | 348,745 | 2.0 | 2.0 | UNSTABLE |
| GRENADA, MS-MONTGOMERY, MS -HSA# 502 | 3 | 134,339 | 2.2 | 2.0 | UNSTABLE |
| WARREN, MS-MADISON, LA -HSA# 431 | 4 | 221,328 | 1.8 | 1.9 | UNSTABLE |
| HARRISON (BILOXI), MS-HANCOCK, MS -HSA# 456 | 10 | 685,416 | 1.5 | 1.6 | UNSTABLE |
| UNION, MS-TIPPAH, MS -HSA# 482 | 3 | 207,692 | 1.4 | 1.4 | UNSTABLE |
| ALCORN, MS-TISHOMINGO, MS -HSA# 498 | 2 | 153,802 | 1.3 | 1.2 | UNSTABLE |
| JACKSON (PASCAGOULA), MS-GEORGE, MS -HSA# 471 | 4 | 444,743 | 0.9 | 1.2 | UNSTABLE |
| ST. TAMMANY (SLIDELL), LA-WASHINGTON, LA -HSA# 500 | 8 | 817,859 | 1.0 | 1.0 | UNSTABLE |
| LAFAYETTE, MS-CALHOUN, MS -HSA# 459 | 2 | 184,774 | 1.1 | 0.7 | UNSTABLE |
