| | 1996-98 | Rate/100,000 | |
| Name | Deaths | Population | Crude | Age Adjusted | |
| OKMULGEE, OK-OKFUSKEE, OK -HSA# 529 | 597 | 148,967 | 400.8 | 320.9 |
| CUSTER, OK-WASHITA, OK -HSA# 475 | 426 | 112,047 | 380.2 | 307.1 |
| PITTSBURG, OK-PUSHMATAHA, OK -HSA# 466 | 771 | 194,570 | 396.3 | 301.2 |
| BECKHAM, OK-ROGER MILLS, OK -HSA# 440 | 278 | 69,534 | 399.8 | 299.3 |
| GRAYSON (SHERMAN), TX-BRYAN, OK -HSA# 436 | 1,950 | 529,055 | 368.6 | 293.5 |
| GRADY, OK-CADDO, OK -HSA# 476 | 693 | 228,485 | 303.3 | 270.8 |
| SEBASTIAN (FORT SMITH), AR-CRAWFORD, AR -HSA# 421 | 2,595 | 895,117 | 289.9 | 269.2 |
| PONTOTOC, OK-SEMINOLE, OK -HSA# 478 | 851 | 238,896 | 356.2 | 263.1 |
| MUSKOGEE, OK-CHEROKEE, OK -HSA# 445 | 1,628 | 604,166 | 269.5 | 260.0 |
| KAY (PONCA CITY), OK-OSAGE, OK -HSA# 515 | 817 | 268,149 | 304.7 | 252.2 |
| LAMAR, TX-RED RIVER, TX -HSA# 438 | 805 | 238,538 | 337.5 | 249.9 |
| TULSA (TULSA), OK-CREEK, OK -HSA# 414 | 5,428 | 2,251,754 | 241.1 | 247.5 |
| CARTER, OK-MARSHALL, OK -HSA# 474 | 717 | 225,439 | 318.0 | 244.8 |
| BOWIE (TEXARKANA), TX-MILLER, AR -HSA# 404 | 1,939 | 721,066 | 268.9 | 239.5 |
| WOODWARD, OK-ELLIS, OK -HSA# 469 | 325 | 103,480 | 314.1 | 237.8 |
| OKLAHOMA (OKLAHOMA CITY), OK-POTTAWATOMIE, OK -HSA# 417 | 5,690 | 2,511,880 | 226.5 | 235.2 |
| JACKSON, OK-GREER, OK -HSA# 483 | 297 | 116,749 | 254.4 | 229.0 |
| COMANCHE (LAWTON), OK-KIOWA, OK -HSA# 493 | 832 | 407,986 | 203.9 | 225.2 |
| PAYNE, OK-PAWNEE, OK -HSA# 472 | 609 | 276,708 | 220.1 | 223.9 |
| GARFIELD (ENID), OK-KINGFISHER, OK -HSA# 429 | 974 | 325,519 | 299.2 | 216.4 |
| STEPHENS, OK-JEFFERSON, OK -HSA# 497 | 449 | 149,964 | 299.4 | 213.2 |
| CLEVELAND (NORMAN), OK-GARVIN, OK -HSA# 430 | 1,305 | 787,628 | 165.7 | 212.4 |
| BEAVER, OK -HSA# 535 | 44 | 17,898 | 245.8 | 207.0 |
| SEWARD, KS-TEXAS, OK -HSA# 587 | 247 | 133,183 | 185.5 | 206.8 |
| WASHINGTON, OK-MONTGOMERY, KS -HSA# 451 | 900 | 306,835 | 293.3 | 201.9 |
| WASHINGTON (FAYETTEVILLE), AR-BENTON, AR -HSA# 446 | 1,922 | 959,828 | 200.2 | 198.5 |
