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NHLBIHIN

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National Cholesterol Education Program

Adult Treatment Panel III (ATP III) Guidelines Slide Set

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SLIDE 1: ATP III Guidelines
Population Groups

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SLIDE 2: Special Considerations for Different Population Groups
Younger Adults

  • Men 20-35 years; women 20-45 years
  • Coronary atherosclerosis accelerated by CHD risk factors
  • Routine cholesterol screening recommended starting at age 20
  • Hypercholesterolemic patients may need LDL-lowering drugs

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SLIDE 3: Special Considerations for Different Population Groups (continued)
Older Adults

  • Men greater than or equal to65 years and women greater than or equal to75 years
  • High LDL and low HDL still predict CHD
  • Benefits of LDL-lowering therapy extend to older adults
  • Clinical judgment required for appropriate use of LDL-lowering drugs

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SLIDE 4: Special Considerations for Different Population Groups (continued)
Women (Ages 45-75 years)

  • CHD in women delayed by 10-15 years (compared to men)
  • Most CHD in women occurs after age 65
  • For secondary prevention in post-menopausal women
    • Benefits of hormone replacement therapy doubtful
    • Benefits of statin therapy documented in clinical trials

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SLIDE 5: Special Considerations for Different Population Groups (continued)
Middle-Aged Men (35-65 years)

  • CHD risk in men > women
  • High prevalence of CHD risk factors
  • Men prone to abdominal obesity and metabolic syndrome
  • CHD incidence high in middle-aged men
  • Strong clinical trial evidence for benefit of LDL-lowering therapy

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SLIDE 6: Special Considerations for Different Population Groups (continued)
Racial and Ethnic Groups

  • Absolute risk for CHD may vary in different racial and ethnic groups
    Relative risk from risk factors is similar for all population groups
  • ATP III guidelines apply to:
    • African Americans
    • Hispanics
    • Native Americans
    • Asian and Pacific Islanders
    • South Asians

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Archived page, reproduced from a 2012 copy. It is reference material, not current guidance.